A large number of previous studies have analyzed clinicopathologic factors associated with prognosis among HCC patients undergoing LT.[22–24] Various factors such as tumor size, tumor number, Milan criteria, AJCC stage, Edmondson–Steiner Grade, AFP, or microvascular invasion have been confirmed to be associated with long-term prognosis.[25–28] In this study, we identified several factors associated with poor DFS by the Kaplan–Meier analysis. The gene discussed is AFP; the disease is hepatocellular carcinoma.