Analysis of miR-10b expression in breast cancer cells at different stages of malignancy revealed a direct correlation between c-Jun and miR-10b expression: Similarly to c-Jun, expression of miR-10b in metastatic breast cancer cells (Hs578T, MDA-MB-231) was considerably higher than that in non-metastatic cells (MCF-7, HCC1937) (Figure 5C). This evidence concerns the gene JUN and breast cancer.