It belongs to the AP-1 transcription factor family, known to upregulate the expression of genes involved in the cell cycle machinery, downregulate the expression of tumor suppressors and contribute to the migration and invasion processes through induction of genes such as matrix metalloproteinases (MMPs) [1, 2], Conditional inactivation of the c-Jun gene, or inhibition of c-Jun/AP1 activity by the addition of dominant-negative c-Jun (TAM67), or siRNA, inhibit cell proliferation and suppress the invasive ability of tumor cells [3, 4]. Here, FOS is linked to neoplasm.