STMN1 and lung adenocarcinoma: As shown in Figure 4C, Transwell assay revealed that the invasion number of stathmin- shRNA (17.67±1.53) group was remarkably decreased compared with the blank (60.33±3.76) and NC (54.00±4.58) groups (p<0.05) (Figure 4D and Table 2), which suggested that downregulation of stathmin blocked the mobility and migration of lung adenocarcinoma cells.