As shown in Figure 5A, the number of DAPI+/CK+/CD45- CTCs captured in 2 mL RCC patient blood (12.8 ± 6.9, n=76) was significantly higher, with a 7.5-fold increase over that obtained from benign patients (1.7 ± 1.7, n=10), including angiomyolipoma, renal adenoma and fibroma. This evidence concerns the gene PTPRC and renal adenoma.