LY6K and breast cancer: The concordance was also breast cancer cell lines with BSP methylation of 13 CpG sites within CGI shore demonstrating 18% and 21% in LY6K-positive MCF7-ADR and MB-436 cells, and 60% and 71% in LY6K-negative T47D and ZR-75-1 cells, whereas the estimated percentages of methylation determined by MCA were 14%, 26%, 68% and 85%, respectively (Figures 3D and 3E).