FOXM1 and neoplasm: Western blot and qRT-PCR analyses showed that compared with either FOXM1 knockdown or gefitinib monotherapy group, the expressions of FOXM1, MET and pAKT were significantly decreased in the FOXM1 knockdown plus gefitinib treatment group, which was further confirmed by immunohistochemical examination of xenograft tumor sections (Figure 6D–6F).