In addition, miR-125b has been shown to induce dexamethasone resistance in MM cells by upregulating miR-34a and suppressing SIRT1 deacetylase thus allowing maintained acetylation and inactivation of p53 through the p53/miR-34a/SIRT1 signaling network [42]. The gene discussed is TP53; the disease is Miyoshi myopathy.