KRAS and colorectal carcinoma: When the expression of miR-450b-5p in CRC was analyzed using published miRNA microarray datasets (NCBI/GEO/GSE28364; n=80), an interesting result was found that the miR-450b-5p was significantly higher in KRAS mutant CRC samples than that in KRAS wild CRC samples (Supplementary Figure S2, P<001, n=40), which was proved by Q-PCR in CRC tissue samples (Figure 2A, P<001, n=83).