TNFRSF10B and neoplasm: The tumor volume of the mice treated with the DTIC-NPs-DR5 mAb formulation was significantly reduced compared to the DITC+ DR5 mAb (p<0.05), indicating that this pharmaceutical engineering not only obtained the combined antitumor effect of DITC+ DR5 mAb, but that active targeting of the delivery carrier provided an additional advantage.