A RANBP2-ALK fusion gene combined with monosomy 7 may be responsible for a certain type of hematologic disorder, such as acute myelomonocytic leukemia, and be related to a poor prognosis.10, 11 Clinical data for our patient and five other previously reported patients5, 10, 11 showing a myeloid neoplasm with ALK rearrangement are summarized in Table 1. Here, ALK is linked to acute myelomonocytic leukemia M4.