Misregulation of DDX3X expression and mutations in the helicase core of DDX3X are associated with tumors, including medulloblastoma, lung- and colorectal cancer and T-cell lymphoma (Bol et al., 2015; Heerma van Voss et al., 2015; Jiang et al., 2015; Pugh et al., 2012). The gene discussed is DDX3X; the disease is T-cell non-Hodgkin lymphoma.