CXCL10 and myeloid sarcoma: Because a tetrac formulation that acts exclusively at integrin αvβ3 stimulates transcription of the CXCL10 gene (Figure 1), the thyroid hormone-relevant issue that is raised here is whether thyroid hormone (T4 or T3)—through CXCL10—may be a factor that reduces the aggressiveness of pathogenesis of MS.