TG and central nervous system cancer: The integrin is generously expressed by nervous system tumor cells, for example, glioma [9] and glioblastoma cells [10], and proliferation of these cells is stimulated via αvβ3 by L-thyroxine, the principal secretory product of the thyroid gland, and, to a lesser extent, by 3,5,3′-triiodo-L-thyronine (T3), which is derived from T4 by deiodination and is the form of thyroid hormone that is active intracellularly.