PLA2R1 and chronic kidney disease: In May 2012, we gave RTX (two doses of 375 mg/m2 every 2 weeks, off label use, low doses as proposed previously) according to promising data form Cravedi et al. [37] and MPD (4 mg daily, to prevent anti CD20-antibody immunization) in PLA2R1 related MN in an attempt to control NS and CKD progression.