Normal human keratinocytes were treated with PMA or DNase I alone, or co-cultured for 16 hours with unstimulated control neutrophils (n = 11), control neutrophils stimulated with PMA (n = 11), control neutrophils treated with both PMA and DNase I (n = 11), unstimulated eczema neutrophils (n = 7), eczema neutrophils stimulated with PMA (n = 7), eczema neutrophils treated with both PMA and DNase I (n = 7), psoriatic neutrophils (n = 9), and psoriatic neutrophils treated with DNase I (n = 9). Here, DNASE1 is linked to Eczematoid dermatitis.