SOX2 and cancer: We next performed deep-targeted sequencing of the 2 Mb region flanking the SOX2 gene locus and BB1 to BB6 on tumor samples from 33 patients with HGSOCs, including case 11152 (Table 1, Supplementary Table 2), and identified 861 single nucleotide polymorphisms (SNPs) in this region (Supplementary Table 5) that were not previously reported in the 1000 Genomes Project (median = 21, range = 11 to 97 per cancer sample).