IFNA2 and cryohydrocytosis: These results were relevant with the study of Gerkens [16] that showed cost-effectiveness of pegylated interferon alpha 2a plus ribavirin in the treatment of CHC genotypes 1 and 6 comparing to the palliative care in Belgium and the study of Gheorghe [17] that showed cost-effectiveness of pegylated interferon alpha 2a plus ribavirin over pegylated interferon alpha 2b, and standard interferon and ribavirin combination in Romania.