The Brca2G25R/Ko;Palb2Ko/+ animals that result in the least interaction between BRCA2 and PALB2 and exhibited the shortest tumor latency, predominantly developed lymphoblastic T-cell lymphomas, similar to the mice carrying a truncating mutation in exon 11 of Brca2 [36, 37]. The gene discussed is PALB2; the disease is neoplasm.