NPPB and chronic kidney disease: Blood cardiac biomarkers, such as cardiac troponins and B-type natriuretic peptide (BNP) have been used in the diagnostics of heart failure [10], but other diseases have also been associated with increased troponin release [e.g. acute pulmonary embolism [11], and end-stage renal disease [12] and/or BNPs [e.g. end-stage renal disease [13].