MMP2 and hypertensive disorder: Concentrations of MMP-2 in PHTN 38.31 ± 9.12 ng/mL and HTN 36.22 ± 9.56 ng/mL were significantly higher compared to N 27.62 ± 6.94 ng/mL (F = 12.71, p < 0.002 and F = 8.41, p < 0.007) (Figure 2).