Concentrations of MMP-9 in PHTN 49.60 ± 12.37 ng/mL and HTN 35.55 ± 10.25 ng/mL were significantly higher compared to N 21.86 ± 7.47 ng/mL (F = 59.35, p < 0.0001 and F = 19.78, p < 0.0002). This evidence concerns the gene MMP9 and hypertensive disorder.