Interestingly, ACOXL contains two risk loci for CLL (Di Bernardo et al., 2008; Berndt et al., 2013), one of which (rs13401811 [Berndt et al., 2013]) maps to a smaller EBNA3A/B/C binding peak between enhancers 1 and 2 that we did not characterise in this study. This evidence concerns the gene ACOXL and B-cell chronic lymphocytic leukemia.