IL1RAPL1 and cancer: Since a validated candidate has not been indicated before, a better understanding of the role of miR-34a-5p and its role in fibrogenesis is urgently required given the recent development of MRX34, a miR-34 analogue now in phase 1 clinical trial for the treatment of cancer [36, 37] and the existence of a miR-34 inhibitor [38].