In the stratification analyses with age, elevated risk of HCC associated with the GLB1 rs4678680 TG or GG genotype was only observed among individuals aged older than 57 years (Shandong set: OR = 1.63, 95% CI = 1.01–2.62; P = 0.047), but not among individuals aged 57 years or younger (Shandong set: OR = 1.46, 95% CI = 0.96–2.21; P = 0.076) (Table 3). The gene discussed is GLB1; the disease is hepatocellular carcinoma.