SNCA and nervous system disorder: Moreover, bioluminescence imaging of all intraperitoneally inoculated mice revealed increased radiance (>2 × 106 p/s/cm2/sr) from the brains of Tg(M83+/−:Gfap-luc+/−) mice injected with α-synuclein fibrils shortly before they developed signs of neurologic disease, but there was no increased radiance from the brains of mice injected with PBS (Fig. 8E and F).