Pathways in cancer, ErbB signalling pathway, insulin signalling pathway, adipocytokine signalling pathway, focal adhesion, renal cell carcinoma, aldosterone‐regulated sodium reabsorption, neurotrophin signalling pathway, Fc gamma R‐mediated phagocytosis and TGF‐beta signalling were co‐regulated by hsa‐miR‐4324, hsa‐miR‐203a, hsa‐miR‐199b‐5p in stage I of NPC (Table 3). The gene discussed is BDNF; the disease is hereditary clear cell renal cell carcinoma.