CSNK1A1 and melanoma: To identify the role of the different CK1 isoforms during melanoma progression we analyzed in this study a) the expression of the CK1 isoforms in melanoma cells of different progression stages in vitro and in vivo, b) the reciprocal influence of CK1 isoform expression for the α, δ and ε family members and c) the functional effects of gene expression modulation of individual CK1-isoforms (alpha, delta and epsilon) on melanoma cell survival, proliferation, migration and invasion.