To address whether Ku70 depletion induces cell death in cell types other than SH-SY5Y cells, we knocked down Ku70 using Ku70 siRNA in several cancer cell lines: N-type NB cells (SH-SY5Y), stromal-type (S-type) NB cells (SHEP-1), ovarian cancer cells (A2780 and ES2), and HEK-293T. The gene discussed is XRCC6; the disease is ovarian carcinoma.