PLA2G7 and cancer: To examine the ability of other cancer cell types to induce PLA2G7 expression by monocytes/macrophages, we co-cultured THP-1 cells with two colorectal cancer (CRC) cell lines (HCT116 and SW480), one breast cancer cell line MCF7 and one non-small lung cancer cell line H1299 in a non-contact co-culture system.