We chose the U138MG cell line, showing expression of all four integrins, the glioblastoma cell lines LN229 and LN308, expressing αVβ3 and α4β1, but are characterized by a different p53 status [19, 20] and the U87MG cell line expressing αVβ3 and αVβ5, also used in the xenograft model. This evidence concerns the gene TP53 and glioblastoma.