The HCC cells with highly invasive potential (HCCLM3 and MHCC97-H) and HCC cells with lowly invasive potential (HepG2) were transfected with corresponding plasmid, and the YMO1 expression was confirmed by RT-PCR and western blot analysis (Figure 3A, Supplementary Figure S5A). Here, EPB41L5 is linked to hepatocellular carcinoma.