In addition, correlation analyses revealed that microRNA-141 significantly correlated with the expression of CTNNAP1 and CTNNA1 in the CRC tissues (P<0.001, R2=0.317 for CTNNAP1; P<0.001, R2=0.304 for CTNNA1) (Figure 2B). The gene discussed is CTNNA1; the disease is colorectal carcinoma.