To verify whether the negative correlation between miR-615-5p and RAB24 also exists in our mouse xenograft model, we isolated RNA and total protein of metastatic tumors in nude mice and found that the mRNA and protein level of RAB24 increased when miR-615-5p expression was blocked (Figure 5E), indicating that RAB24 is a direct and functional target of miR-615-5p. The gene discussed is RAB24; the disease is metastatic neoplasm.