Estrogen Receptor-negative Breast Cancer, Extensive Stage Small Cell Lung Cancer, HER2-negative Breast Cancer, HER2-positive Breast Cancer, Male Breast Cancer, Recurrent Breast Cancer, Recurrent Melanoma, Recurrent Non-small Cell Lung Cancer, Recurrent Small Cell Lung Cancer, Stage IV Breast Cancer, Stage IV Melanoma, Stage IV Non-small Cell Lung Cancer, Tumors Metastatic to Brain, Unspecified Adult Solid Tumor. This evidence concerns the gene ESR1 and breast cancer.