SMARCA4 and neoplasm: Similarly, after a comparison of qPCR values for BRG1-deficient tumors with wild type control DNA, only one tumor showed a statistically significant difference (p = 0.001), where the ΔΔCT was equal to 1.85, which is consistent with focal biallelic loss of BRG1. The other 19 BRG1-deficient tumors had ΔΔCT < 0.09 (p values > 0.5-0.7) with no detectible BRG1 allelic loss.