Similarly, Oike et al. analyzed 101 cases of NSCLC, where 16 (13%) were found to be BRG1-deficient; additionally, the sequencing of the genomic DNA from the 16 tumors for BRG1 revealed that none of these tumors harbored any abrogating mutations [31]. The gene discussed is SMARCA4; the disease is non-small cell lung carcinoma.