Another group co-delivered fibroblast growth factor-1 (FGF-1) and NRG to treat the MI heart by loading them into poly (lacto-co-glycolic acid) microparticles, and observed that this treatment reduced infarct size and increased scar thickness leading to superior mechanical properties of the recovering heart (Formiga et al., 2014). The gene discussed is FGF1; the disease is myocardial infarction.