Among the most prominent kinases involved in TAU hyperphosphorylation in AD are ERK1/2, CDK5, and GSK3B (Mandelkow et al, 1995), and in silico analysis (Targetscan 7.0) predicts ERK1, ERK2, GSK3b, and TAU itself as putative miR‐132 targets in human and mouse. This evidence concerns the gene CDK5 and Alzheimer disease.