To date mutations in Forkhead Box C1 (FOXC1, OMIM 601090), Paired-Like Homeodomain transcription factor 2 (PITX2, OMIM 601542), and Paired Box Gene 6 (PAX6, OMIM 607108) genes are the most common cause of glaucoma in ASD [8]. The gene discussed is PITX2; the disease is glaucoma.