Our previous study showed that in ovarian carcinoma cell lines OVCA433 and OVCR3, introduction of a dominant negative mutant IĸBα (IĸBαM), which constitutively suppresses NF-kB function, resulted in cell proliferation and inhibition of apoptosis through ERK/MAPKs pathway. This evidence concerns the gene NFKB1 and ovarian carcinoma.