These include mutations in myotubularin 1 (MTM1) and myotubularin-related protein 14 (MTMR14) that are associated, respectively, with X-linked myotubular myopathy (Laporte et al. 1997) and congenital disease centronuclear myopathy (Tosch et al. 2006). This evidence concerns the gene MTM1 and X-linked myotubular myopathy.