Ccl24 (eotaxin-2), which functions as a potent eosinophil and granulocyte chemoattractant in vivo in both atopic and nonatopic patients28 and in animal models of airway allergy,29, 30 was approximately 5.7-fold upregulated in Map3k8−/− DCs compared with WT DCs (Fig 5, G). This evidence concerns the gene CCL24 and allergic respiratory disease.