PVT1 and asthma: We have then focused on the only lncRNA found to be decreased in expression in patients with corticosteroid-sensitive nonsevere asthma and increased in expression in patients with corticosteroid-insensitive severe asthmatics, plasmacytoma variant translocation 1 (PVT1), and performed targeting studies to examine its role in a corticosteroid insensitivity model in these cells induced by the combination of TGF-β and FCS.