RBFOX3 and Stroke: This result highlights the importance of measuring functional outcomes of recovery rather than lesion size as an index of recovery in preclinical animal studies, similar to what is done in clinical stroke studies.77, 81 Because after 6 weeks the behavioral phenotype did not improve, the NeuN-expressing neurons that infiltrated the stroke lesion did not appear to be integrated into the behavioral circuitry, and this could be verified using electrophysiological analysis.