Anaplastic lymphoma kinase (ALK) is a clinical target of major interest in adult cancers characterized by chromosomal translocations (Hallberg and Palmer, 2013) in which the ALK kinase domain is fused to an array of amino-terminal partners, such as EML-4 (Rikova et al., 2007; Soda et al., 2007) in non-small cell lung cancer (NSCLC) (Awad and Shaw, 2014), or NPM (Morris et al., 1994) in anaplastic large cell lymphoma (ALCL). This evidence concerns the gene ALK and anaplastic large cell lymphoma.