ALK and neuroblastoma: Given the accumulated basic knowledge concerning ALK mutants in neuroblastoma (Hallberg and Palmer, 2013 and references therein), and the potential that one of the newly developed ALK inhibitors could be effective for the neuroblastoma patient population, we aimed to explore next-generation ALK inhibitors in the preclinical setting, with a focus on PF-06463922 (lorlatinib).