SEMA5A and autism spectrum disorder: FOXP2 plays a role in neurogenesis and is involved in language and speech disorders (Chiu et al., 2014; Roll et al., 2010; Tsui et al., 2013) SEMA5A, which encodes members of the semaphorin family, has been implicated in axonal guidance and is a candidate gene in autism spectrum disorder (Cheng et al., 2013; Melin et al., 2006).