EGCG also plays important roles in inhibiting tumor metastasis through the modulation of signaling pathways, including the modulation of β1 integrin-mediated signaling [74], down regulation of vasodilator-stimulated phosphoprotein (VASP) expression via the Rac1 pathway [72], enhancing the expression of α1-antitrypsin by regulating the PI3K/AKT pathway [75], and down-regulating the EGFR signaling pathway [76]. This evidence concerns the gene VASP and neoplasm.