SP110 and tuberculosis: Mounting evidence that type-I-interferon signaling pathways are upregulated in active TB (Berry et al., 2010), as well as evidence associating TB with polymorphisms in SP110, the closest human homolog of the candidate Ipr1 gene of the mouse sst1 locus, indicates the likely relevance of this mouse strain (Abhimanyu et al., 2011; He et al., 2013; Tosh et al., 2006).