Moreover, several groups have shown that mice with transgenic expression of TERT have a higher susceptibility to develop tumours in the absence of telomere length differences (Artandi et al., 2002; Canela et al., 2004; González-Suárez et al., 2001) and that this effect is dependent on the presence of TERC (Cayuela et al., 2005). The gene discussed is TERT; the disease is neoplasm.