Five gene networks were extracted by IPA: Network 1 consisted of genes related to cancer and cell-cycle arrest, such as Bax, Btg2, Ccng1, Cdkn1a, Gadd45b, Gdf15, Hspb1, Hspb2, Mdm2, Plk2, and Pmm1; Network 2 comprised cell cycle, DNA replication and recombination, repair, and cell death genes, such as Ccng2, Cyp1a2, Cyp4a10, Cyp21a1, Gdf15, Ppp1r3c, Rcan1, and Tubb4b (Tubb2c). This evidence concerns the gene GADD45B and cancer.