RBFOX1 and atrial septal defect 8: Array comparative genomic hybridization (aCGH) and genome-wide linkage studies (GWAS) have demonstrated that RBFOX1 is associated with autism ASD8, 9, 10, 11, 12, 13, and chromosome region 16p13, where RBFOX1 is located, was identified as the location of ASD-implicated genes14, 15.