DDN and cancer: The identified gained regions contain TRIB2, MFI2, RET, WNT1, DDN, PRKAG1, KMT2D, RUNX1, BRWD3, GRIA3, and XIAP. All these genes are known to be involved, at least to a certain degree, in different types of cancer: based on our findings, we suggest that they might have a critical role also in colorectal cancer onset and progression.