As shown in Table 2 and Fig. 1B, NOS1 was overexpressed in the DCM samples compared to the CNTs, while we did not find similar changes in NOS2 and NOS3. Important NOS1-related genes such as GCH1 and ATP2A2 had significantly decreased mRNA levels in the DCM samples, while mRNA levels of SPR, DYNLL1, ATP2A3, and RyR3 were upregulated. The gene discussed is SPR; the disease is familial dilated cardiomyopathy.